马来西亚私立医院抗高血压药物处方实践:一项前瞻性、非干预性观察研究

01 May 2023


WK Ng, AZ Philip, TT Lim, M Wong, EL Goh, TS Tengku Ismail, TH Goh

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摘要

Introduction: 

In managing hypertension, monotherapy and sometimes a combination of more than one agent are used to achieve blood pressure (BP) control. The objective of this prospective, observational, multi-centre study was to assess the level of BP control in patients receiving one or more anti-hypertensive drugs in private medical centres in Malaysia according to the treatment regimens (monotherapy, free drug combinations and single pill combinations).

Materials and methods: 

Data were collected through medical records and interview sessions with patients on current pharmacotherapy for hypertension management at baseline and 2-3 months later. Results are expressed as mean ± SD for continuous data and as frequencies and percentages for categorical data.

Results: 

Among 182 recruited patients, 89 (49%) achieved BP control by the end of the study. Majority (62/89) patients were on single-pill (monotherapy or SPC) antihypertensives. Majority (63/89) required more than two antihypertensives to achieve BP control.

Conclusion: Both SPC and free drug combination antihypertensives reduced BPs, but physicians preferred SPC to improve BP control and increase treatment compliance.


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引用

Ng, W. K., Philip, A. Z., Lim, T. T., Wong, M., Goh, E. L., Tengku Ismail, T. S., & Goh, T. H. (2023). Anti-hypertensive prescription practices in private hospitals in Malaysia: a prospective, non-interventional, observational study. The Medical journal of Malaysia78(3), 350–356.

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