Guillain-Barré syndrome (GBS) is a heterogeneous disorder with factors related to geography that have a major influence on clinical phenotype, disease severity, electrophysiological subtype, and outcome.[¹] During the recent Zika virus epidemic, many expected a sharp rise in the number of GBS cases in Asia, just like what was reported in Latin America.[²³] Intriguingly, Asian countries have not seen a similar spike in GBS cases linked to Zika virus even in a region with a high incidence of GBS, suggesting the unique geographical differences.[⁴⁵] Since the beginning of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic in March 2020 and subsequent reports of cases with neurological manifestations linked to SARS-CoV-2 virus, the number of GBS cases has been in the spotlight and closely monitored across the world.[⁶⁷]

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