Pleuroperitoneal Fistula, an Unusual Case of Recurrent Unilateral Transudative Pleural Effusion

25 June 2026


Collin Kah Jing Lo, Yi-De Ng, Grace Sook Hoon Low, Leng Cheng Sia


Abstract

A 39-year-old woman afflicted by systemic lupus erythematous (SLE) with musculoskeletal involvement and end-stage renal failure (ESRF) on continuous ambulatory peritoneal dialysis (CAPD) presented with recurrent left-sided transudative pleural effusion. Guided by the ratio of pleural glucose to serum glucose > 1, and further confirmatory tests via a targeted imaging study, we were able to secure the diagnosis of a pleuroperitoneal leak. This case report highlighted the finding of this uncommon diagnosis that, if missed, would be detrimental to the patient's care.

Keywords

end stage renal failure; glucose gradient; peritoneal dialysis; pleural effusion; pleuroperitoneal fistulae.


Reference

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Cite

C. K. J. Lo, Y.-D. Ng, G. S. H. Low, and L. C. Sia, “ Pleuroperitoneal Fistula, an Unusual Case of Recurrent Unilateral Transudative Pleural Effusion,” Respirology Case Reports 14, no. 7 (2026): e70655, https://doi.org/10.1002/rcr2.70655.

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