Systemic Lupus Erythematosus (SLE), commonly known as lupus, is a chronic autoimmune condition that causes inflammation in various body parts, including joints, skin, kidneys, and nerves. It occurs when the immune system erroneously attacks healthy cells and tissues.

What Causes Systemic Lupus Erythematosus?

The exact cause of SLE is not yet known. Researchers suggest several potential triggers:

  • Genetic predisposition
  • Environmental factors, such as ultraviolet radiation from sunlight and stress
  • Viral or other infectious diseases
  • Certain medications like methyldopa, procainamide, hydralazine, isoniazid, chlorpromazine

Symptoms of Systemic Lupus Erythematosus

SLE affects individuals differently, with symptoms ranging from mild to severe and varying in affected body parts. Some common symptoms include:

  • Joint swelling and pain
  • Fever
  • Sunlight-exposed skin rash, particularly on the nose and cheeks
  • Extreme fatigue
  • Hair loss
  • Chest pain and difficulty breathing
  • Kidney inflammation, bloody or foamy urine, high blood pressure
  • Blood cell abnormalities
  • Sensitivity to sunlight
  • Mouth and nose sores
  • Swollen lymph nodes
  • Headaches, dizziness, seizures
  • Muscle inflammation and weakness
  • Pleura and heart inflammation
  • Chronic dry eyes and mouth

Treating Systemic Lupus Erythematosus

Currently, there's no cure for lupus, but its symptoms can be managed with lifestyle adjustments and proper medication. Treatment varies based on severity:

  • For mild symptoms: symptom-alleviating medication
  • For severe symptoms affecting major organs: immunosuppressant medication
  • Long-term treatment and continuous medication, even in symptom-free periods, are often required.

Preventing Flare-Ups in Systemic Lupus Erythematosus While SLE can't be prevented due to unknown causes, managing it effectively involves:

  • Regular medical check-ups and consistent medication
  • Prompt and aggressive treatment of infections
  • Sunlight avoidance, protective clothing, and high SPF sunscreen
  • Eating a healthy diet and avoiding raw foods
  • Stress management
  • Adequate rest
  • Regular exercise with doctor's approval
  • Immediate medical attention if symptoms recur
  • Avoidance of birth control pills or estrogen replacement


Systemic Lupus Erythematosus is a complex autoimmune disease requiring careful management. Understanding its causes, symptoms, and treatment options is essential for those affected. Regular medical supervision and lifestyle adjustments play a crucial role in managing this condition.